- Transitional cell, or urothelial carcinoma – consists of cells of the inner surface of the bladder. This is the most common type of pathology – about 90% of cases. At the same time, it rarely grows through the walls of the organ or gives metastases.
- Squamous cell – develops from epithelial cells of the same name, which in 75% of cases are formed in the bladder as a result of inflammation and parasitic infection. This is a rather rare type of tumor, common only in tropical countries, and is not typical for our region. Squamous cell cancer progresses rapidly and causes distant metastases.
- Adenocarcinoma – consists of cells of the mucous membrane. This is also a rare type, but its peculiarity is that the tumor can be both primary and a metastasis, for example, colon cancer. Therefore, it is necessary to carefully examine the patient to exclude the presence of the disease in other organs.
Bladder cancer treatment
Bladder cancer treatment in Kiev
Bladder cancer is a malignant neoplasm that grows from the wall of the organ. The tumor is more common in men than in women - it occurs 3 times more often in them. People aged 40 to 60 are most susceptible to the disease, as well as those who work in potentially hazardous industries: oil, rubber, paint, aluminum, using plastics, resins, etc.
According to statistics, bladder cancer is a fairly rare oncological pathology and in more than half of cases it is diagnosed in the early stages, which improves the prognosis for treatment.
Forms and stages of bladder cancer
Bladder cancer is classified by the type of cells that make up the tumor, as well as its size, spread to adjacent organs, and the development of metastases.
According to the histological structure (type of tissues involved in the process), 3 types of tumors are distinguished:
Depending on the spread of the pathological process, there are 4 stages of cancer.
- Stage 1 – the tumor develops in one of the layers of the bladder tissue;
- Stage 2 – the tumor size increases, it grows into the muscle layer of the organ;
- Stage 3 – the tumor goes beyond the bladder, grows into fatty tissue, sometimes into nearby lymph nodes.
- Stage 4 – the tumor affects adjacent organs and can metastasize throughout the body.
Symptoms of bladder cancer
A small tumor may not bother the patient for a long time until it increases in size and begins to squeeze neighboring organs.
The main symptoms of bladder cancer are:
- blood in the urine (may become darker or red);
- urination disorders (frequent urges, feeling of incomplete emptying, etc.);
- pain in the lower abdomen, groin, lower back.
The first symptoms in most cases are blood in the urine. Then there are frequent urges to urinate, a feeling of fullness of the bladder, incomplete emptying and other urination disorders. Pain is a later symptom. It can be periodic or constant, localized in the pelvic area, lower back or genitals.
It should be borne in mind that such symptoms can also appear with other diseases of the genitourinary system. An accurate diagnosis can only be made based on the results of an examination - the effectiveness of self-diagnosis based on one's own feelings is close to zero.
Causes and risk factors of bladder cancer
Bladder tumors have statistically proven risk factors. Experts note a significant prevalence of the disease among people who have smoked for many years, worked in chemical plants and inhaled aromatic amine vapors (ammonia derivatives), and have also been subjected to parasitic invasion (schistosomiasis).
Bladder cancer diagnosis
Diagnosis and treatment of malignant diseases of the genitourinary system is the specialization of an onco-urologist. He provides assistance to both men and women.
During the first appointment, the urologist will listen to complaints and ask clarifying questions to better understand the clinical picture. The doctor will also study the medical history: the presence of chronic pathologies, previous infections, previously performed examination or treatment. After that, the specialist will examine the patient and prescribe the necessary examinations.
To clarify the exact diagnosis, the following may be required:
- urine tests;
- blood tests;
- urogenital discharge tests;
- bladder ultrasound;
- cystoscopy;
- biopsy with histological analysis;
- X-ray, CT scan of the abdominal cavity and chest, etc.
A tumor can be diagnosed during an ultrasound, but its type can only be determined by histological analysis of cells. To obtain a sample, an endoscopic examination is performed - cystoscopy. A flexible tube equipped with an optical device and a biopsy tool is inserted into the patient's bladder through the urethra. The image from the microcamera is transmitted to a monitor, which allows the doctor to carefully examine the inner lining of the organ and pinch off a small piece of the tumor for analysis. The procedure is performed under local anesthesia.
Laboratory tests are also of important diagnostic importance. Bladder cancer is characterized by a constant increase in leukocytes in the urine and anemia, but these markers are nonspecific and can be a manifestation of many other diseases
To determine the stage of cancer and check for metastases, an X-ray or CT scan of the abdominal cavity and chest is performed.
Bladder cancer treatment
Comprehensive therapy is used to treat cancer. Its program and duration depend on the stage of the disease and the presence of metastases.
The patient may be prescribed:
surgical treatment - removal of the tumor or bladder;
radiation therapy - irradiation of the tumor with high doses of X-rays or other radiation;
chemotherapy - taking drugs that destroy cancer cells (can be local - drugs are injected into the bladder, or systemic - affects the entire body);
immunotherapy - injection into the bladder of a drug based on the BCG vaccine (for tuberculosis), which provokes the immune system to destroy the tumor.
For small tumors and without metastases, surgery is performed first, and then chemotherapy or other treatment. Postoperative therapy helps destroy cancer cells that may have remained in the body and reduce the risk of relapse.
For large tumors that have spread to nearby organs, radiation therapy may be required initially. In some cases, it can shrink the tumor, making surgery easier.
Oxford Medical employs experienced oncologists who provide conservative and surgical treatment for cancer.
To schedule a consultation, call our contact center or use the chat on our website.
Surgical treatment of bladder cancer
Depending on the size of the tumor, one of 3 operations is performed:
Transurethral resection (TUR) of the bladder
This is the least traumatic operation, which is performed using endoscopic equipment.
Open resection
Access to the bladder is provided through the anterior abdominal wall.
Radical cystectomy
This is surgery to remove the bladder, nearby lymph nodes, and other organs affected by cancer.
Frequently asked questions
How to distinguish cystitis from bladder cancer?
Cystitis is an inflammation of the bladder, while cancer is a malignant disease accompanied by tumor growth. Pathologies have different symptoms and other features, so a urologist can easily distinguish them using ultrasound and other tests.
Does an ultrasound show bladder cancer?
During an ultrasound, a doctor can detect a bladder tumor, but to determine its nature, it is necessary to perform a biopsy (obtain a tissue sample) and perform a histological analysis.
How long does it take for bladder cancer to develop?
Bladder cancer, like other malignant neoplasms, can progress in different ways. Most often, the tumor develops asymptomatically for 1 or more years, but after increasing in size, affecting adjacent organs and lymph nodes, it quickly causes a deterioration in well-being.
What are the risks of bladder cancer?
Bladder cancer is a life-threatening malignant disease. In its early stages, it is well treatable. With a small tumor, partial resection of the bladder is possible while preserving its functionality, while with an increase in size, removal of the entire organ and nearby lymph nodes may be required, which leads to a deterioration in the quality of life.
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