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Treatment of small intestine cancer at the private clinic Oxford Medical Kyiv

Small intestine cancer

Treatment of small intestine cancer in Kiev

Small intestine cancer is a malignant neoplasm that develops in one of its sections:

  • duodenum - departs from the stomach and bypasses the pancreas;
  • jejunum - is the main section that has the greatest length;
  • ileum - connects to the cecum (upper part of the large intestine).

In an adult, the length of the small intestine is from 4.5 to 6 meters. At the same time, due to anatomical and functional features, malignant tumors develop in it extremely rarely - 3-4% of all oncological pathologies of the gastrointestinal tract.

With early diagnosis, small intestine cancer is successfully treated in more than 90% of cases. At stages 2 and 3, five-year survival is 70 and 55%, respectively.

At Oxford Medical, treatment of malignant diseases is carried out by oncologists and oncological surgeons of the highest category with many years of experience. For each patient, they develop an individual therapy program, guided by state and international protocols. The clinic has installed new diagnostic and surgical equipment, and all conditions have been created for chemotherapy and other types of treatment. Thanks to this, each patient receives medical care at the highest level.

Stages of small intestine cancer

The tactics and effectiveness of treatment for small intestine cancer directly depend on the stage at which it was diagnosed. When determining it, the size of the tumor, the depth of the intestinal wall lesion, the presence of metastases in the lymph nodes and distant organs are taken into account. For a detailed classification, oncologists use the international TNM system.

Cancer stages are distinguished:

According to the T criterion, which indicates the size of the tumor

  • T1 – tumor size up to 2 cm, it affects only the intestinal mucosa and has clear boundaries;
  • T2 – tumor more than 2 cm, extends to the muscular layer of the intestine;
  • T3 – tumor covers all layers and extends to the outer wall of the organ;
  • T4 – tumor extends to adjacent organs.

According to the N criterion, which means lymph node involvement

  • N0 – lymph nodes are not affected;
  • N1 – 1 or 2 nearby lymph nodes are affected;
  • N2 – there are metastases in distant lymph nodes.

According to the M criterion, which means the presence of metastases

The M criterion means the presence of metastases. It has only two values: M0 – no distant metastases and M1 – there are.

According to this classification, the stage of cancer can look like T1N1M0, T2N0M0, T2N1M0, etc. Most patients do not understand this, so it is customary to use a simplified system.

Simplified system

According to it, 5 stages of cancer are distinguished:

  • Stage 0 - preinvasive form of cancer, when malignant cells are localized in the surface epithelium of the inner lining of the intestine;
  • Stage 1 - tumor less than 2 cm, affects the mucous membrane, has clear contours;
  • Stage 2 - tumor more than 2 cm, grows into the muscle layer, metastases in nearby lymph nodes are possible;
  • Stage 3 - the tumor increases, goes beyond the duodenum, affects the lymph nodes;
  • Stage 4 - the tumor is large, spreads to neighboring organs, there are distant metastases.

Types of small intestine cancer

To select therapy, it is important to find out both the stage and the type of malignant neoplasm.

Depending on the localization, they are distinguished:

  1. Exophytic cancer - a tumor located in the lumen of the intestine. It looks like a polyp, plaque or fungus on a thin leg. If it increases in size, it can cause blockage.
  2. Endophytic cancer - a tumor develops in the intestinal wall. It has no visible contours, which makes removal difficult, and can lead to rupture of the wall.

Also, according to the results of histological analysis (cell type), they are distinguished:

  1. Adenocarcinoma - develops from glandular tissue cells.
  2. Sarcoma consists of immature cells of muscle, adipose, connective or vascular tissue.
  3. Lymphoma - develops from components of lymphoid tissue.
  4. Carcinoma - consists of altered epithelial cells.
  5. Melanoma – develops from cells that contain the pigment melanin (rare among tumors of the gastrointestinal tract);
  6. Schwannoma – consists of nerve fiber cells.

Symptoms of small intestine cancer

If several symptoms appear, you should consult a doctor and undergo diagnostics.
But do not forget that other diseases also manifest themselves in this way, so the probable
diagnosis may not be confirmed.

Small intestine tumors develop asymptomatically for a long time. In most cases
they are discovered by chance when the patient undergoes
a check-up or consults a doctor for another reason.

However, as the neoplasm increases, the following symptoms may appear:

change in stool color, blood impurities

diarrhea

heartburn, belching

decreased appetite

nausea and vomiting

stomach ache

sudden weight loss

general weakness

slight increase in temperature over a long period of time

List of diseases

Diagnosis of small intestine cancer

To diagnose the disease, laboratory and instrumental studies are performed.

After conducting an examination, studying complaints and anamnesis, the doctor may prescribe:

  • general blood and urine tests;
  • blood biochemistry;
  • blood test for tumor markers;
  • stool analysis for occult blood;
  • endoscopic examination of the intestine;
  • X-ray of the intestine with the use of a contrast agent;
  • biopsy - tissue sample collection (performed during endoscopy);
  • histological analysis;
  • immunohistochemical analysis;
  • ultrasound, CT, MRI and other examinations according to indications.

The most accurate diagnostic method is endoscopic examination. It involves the introduction of an endoscope into the small intestine - a small elastic tube equipped with a video camera. As it moves through the gastrointestinal tract, it transmits the image to the monitor screen, where it is magnified many times. This allows the doctor to carefully examine the mucous membrane and detect any changes and neoplasms. In the latter case, a biopsy is performed immediately - a small piece of tissue is removed for histological analysis. This is used to determine the type of cells and the malignancy of the tumor.

Other studies are prescribed to determine the stage of the cancer, the presence of distant metastases, and to assess the patient's general health.

Treatment of small intestine cancer

Oxford Medical employs oncologists and oncological surgeons of the highest category with many years of experience. Many are rightfully considered the best in Kyiv and throughout Ukraine. Thanks to this, as well as the availability of expert-class equipment in the clinic, we provide each patient with medical care that meets the highest quality standards.

The clinic operates a modern surgical hospital with 2 operating rooms, an intensive care unit and an intensive care unit. This allows us to perform operations of any complexity.

Surgical treatment is key for small intestine cancer. If the tumor is detected at stage 0-2, surgery is usually performed first. Surgeons remove the tumor or part of the intestine, after which the ends are sewn together. For large tumors, the volume of manipulations increases accordingly.

After surgery, based on the results of tests and other diagnostics, the doctor may prescribe chemotherapy, radiation therapy or other treatment to eliminate the remaining malignant cells, prevent relapse or treat metastases.

When diagnosing cancer at stage 3-4, sometimes chemotherapy and radiation therapy are also prescribed before surgery to achieve tumor reduction and radical removal.

Radiation therapy has a local effect. It affects the cells of the neoplasm, slowing their growth and causing tissue destruction.

Chemotherapy has a systemic effect. It affects the entire body, which contributes to the destruction of malignant cells, regardless of their localization. Treatment is carried out with drugs of 2 groups: cytostatic and cytotoxic. The first slow down the processes of cell division, which inhibits the development of cancer, and the second contribute to their destruction. But due to the systemic effect, chemotherapy affects healthy organs, which leads to the development of side effects.

Chemoradiation therapy, targeted and immune therapy are also used for small intestine cancer.

A treatment program is drawn up individually for each patient after a thorough diagnosis.

Oxford Medical has created all the conditions for accurate diagnostics and effective treatment. We employ oncologists and oncological surgeons with many years of experience who are familiar with all modern methods of cancer treatment, including targeted and immunotherapy.

To schedule a consultation, call our contact center or write to the chat on the website.

Risk factors for small intestine cancer

Small intestine cancer is the rarest of all oncological pathologies of the gastrointestinal tract. This is due to anatomical and functional features. In the small intestine, feces have a liquid consistency and are not delayed, which reduces the duration of exposure to carcinogenic substances on its walls. In addition, they are lined with a dense layer of lymphoid tissue, which provides a protective effect.

The disease occurs mainly in patients over 60 years of age. It is diagnosed in men twice as often as in women.

Risk factors are:

  • intestinal polyps;
  • ulcerative colitis;
  • Crohn's disease;
  • hereditary predisposition;
  • diabetes mellitus;
  • obesity;
  • smoking;
  • alcohol abuse;
  • unbalanced diet.

Prevention of small intestine cancer

To reduce the risk of pathology, it is recommended to:

  • eat a healthy diet (eat more vegetables, fruits and whole grains, reducing the amount of semi-finished products and fatty dishes from red meat);
  • maintain a normal weight;
  • give up smoking and alcohol;
  • engage in physical activity;
  • treat all diseases of the gastrointestinal tract in a timely manner;

After 40 years of age, both men and women are recommended to undergo an examination by a proctologist every year. In the event of the development of pathology, this will allow it to be diagnosed at an early stage, when treatment is most effective.

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Frequently asked questions

How is small intestine cancer diagnosed?

The most reliable method of diagnosis is endoscopic examination – it allows to examine the inner lining of the intestine with the help of a miniature video camera, and if a neoplasm is detected, a tissue sample is taken for histological analysis. It determines the type of cells and their malignant nature.

As a primary diagnosis, sometimes an X-ray, CT or MRI scan, as well as blood tests for relevant tumor markers, are performed.

How common is small intestine cancer?

Small intestine cancer accounts for 3-4% of all gastrointestinal tumors. The disease is quite rare due to the peculiarities of the anatomy and functionality of the organ. Feces do not linger in it, as they have a soft or liquid consistency, which eliminates the long-term impact of carcinogenic substances on the walls. This reduces the risk of malignant process.

How quickly does small intestine cancer develop?

In its early stages, small bowel cancer develops very slowly and may not show any symptoms for several years. Screening can help detect it early and treat it when it is most effective. Once it has grown through the intestinal wall and affected lymph nodes, the cancer progresses more quickly. The rate at which it progresses depends on the type of tumor, response to treatment, and overall health.

What is the life expectancy with small intestine cancer?

When diagnosed at stage zero, more than 95% of patients recover completely. At stage 1, 5-year survival reaches 70%, at stage 2 - 55%, at stage 3 - 30%, at stage 4 - 10%.

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Benefits of small bowel cancer treatment at Oxford Medical

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Oncologists and oncological surgeons with many years of experience

High-tech surgical hospital

Intensive care unit (resuscitation), equipped with equipment to support vital body functions

Chemotherapy, targeted therapy, and immunotherapy

Affordable price and loyalty program for regular patients

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